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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3B
All Species:
17.88
Human Site:
S225
Identified Species:
30.26
UniProt:
Q7Z3V4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3V4
NP_569733.2
1068
123070
S225
A
R
P
R
P
C
L
S
K
G
T
L
T
A
A
Chimpanzee
Pan troglodytes
XP_509354
1068
122921
S225
A
R
P
R
P
C
L
S
K
G
T
L
T
A
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543437
1068
123121
S225
A
R
P
R
P
C
L
S
K
G
T
L
T
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES34
1070
122743
S225
A
R
P
R
P
C
L
S
K
G
M
L
T
A
A
Rat
Rattus norvegicus
NP_001137366
1070
122598
S225
A
R
P
R
P
C
L
S
K
S
T
L
T
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423951
837
96057
L74
G
A
S
K
R
S
A
L
S
V
F
R
I
A
R
Frog
Xenopus laevis
Q6DCL5
944
106566
T178
A
C
Q
N
G
H
K
T
T
V
L
C
L
L
D
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
E209
A
F
I
R
E
T
R
E
Q
S
E
P
S
S
G
Honey Bee
Apis mellifera
XP_392283
1063
121439
K224
G
R
V
E
I
A
L
K
P
I
A
L
S
A
A
Nematode Worm
Caenorhab. elegans
NP_499392
1066
120863
L220
S
V
N
G
H
K
P
L
I
N
V
E
T
V
N
Sea Urchin
Strong. purpuratus
XP_786887
582
66877
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWB8
1029
117643
R219
R
K
V
F
K
L
V
R
E
M
V
T
T
A
K
Baker's Yeast
Sacchar. cerevisiae
P53119
910
105547
L147
C
P
T
V
D
E
F
L
D
S
L
S
V
Y
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
N.A.
96.5
N.A.
92.1
91.8
N.A.
N.A.
68.6
20.8
22.8
N.A.
20.4
51.5
37.6
37.1
Protein Similarity:
100
98.9
N.A.
98.5
N.A.
96
96.1
N.A.
N.A.
74
40.1
38.4
N.A.
37.1
69.1
58.4
44.9
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
6.6
6.6
0
N.A.
13.3
33.3
6.6
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
13.3
13.3
0
N.A.
33.3
40
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.7
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.7
42
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
8
0
0
0
8
8
0
0
0
8
0
0
58
36
% A
% Cys:
8
8
0
0
0
36
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
8
% D
% Glu:
0
0
0
8
8
8
0
8
8
0
8
8
0
0
0
% E
% Phe:
0
8
0
8
0
0
8
0
0
0
8
0
0
0
0
% F
% Gly:
15
0
0
8
8
0
0
0
0
29
0
0
0
0
8
% G
% His:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
0
0
8
8
0
0
8
0
0
% I
% Lys:
0
8
0
8
8
8
8
8
36
0
0
0
0
0
8
% K
% Leu:
0
0
0
0
0
8
43
22
0
0
15
43
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
0
0
8
0
0
0
0
8
% N
% Pro:
0
8
36
0
36
0
8
0
8
0
0
8
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
8
43
0
43
8
0
8
8
0
0
0
8
0
0
8
% R
% Ser:
8
0
8
0
0
8
0
36
8
22
0
8
15
8
0
% S
% Thr:
0
0
8
0
0
8
0
8
8
0
29
8
50
0
8
% T
% Val:
0
8
15
8
0
0
8
0
0
15
15
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _